Cryopyrin Antibody, ALEXA FLUOR 555

• Catalog number
  bs-10021R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  Cryopyrin Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-CIAS1 PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CIAS1
• Specificity
  This is a highly specific antibody against CIAS1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  1-50/1036
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Cryopyrin
• Gene ID Number
  114548
• Swiss Prot
  Q96P20
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  NACHT, LRR and PYD domains-containing protein 3; Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1; NLRP3; C1orf7; CIAS1; NALP3; PYPAF1
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• French translation
  anticorps

• Gene target
  Cryopyrin  
• Gene symbol
  NLRP3
• Short name
  Anti-CIAS1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  Cryopyrin Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16400
• Gene
  NLRP3
• Long gene name
  NLR family pyrin domain containing 3
• Synonyms gene
  • C1orf7
  • CIAS1
  • DFNA34
• Synonyms gene name
  • cold autoinflammatory syndrome 1
  • deafness, autosomal dominant 34
• Synonyms
  • AGTAVPRL
  • AII
  • AVP
  • FCAS
  • FCU
  • NALP3
  • PYPAF1
  • MWS
  • CLR1.1
• Synonyms name
  • Cryopyrin
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3
• GenBank acession
  • AF054176
• Locus
  1q44
• Discovery year
  2001-08-28
• Entrez gene record
  114548
• Pubmed identfication
  • 10741953
• RefSeq identity
  • NM_004895
• Classification
  • Pyrin domain containing
  • NLR family
• VEGA ID
  OTTHUMG00000040647
• Locus Specific Databases
  • INFEVERS: The repertory of Familial Mediterranean Fever (FMF) and Hereditary Inflammatory Disorders Mutations
  • LRG_197

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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