anti- MGP antibody

• Catalog number
  FNab05170
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia.
• Immunogen
  matrix Gla protein
• Synonyms
  GIG36, matrix Gla protein, MGLAP, MGP, NTI
• Calculated MW
  12 kDa
• Uniprot ID
  P08493
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:100 - 1:200
• Image1
  Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab05170( MGP antibody) at dilution of 1:200
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MGP  
• Gene symbol
  MGP
• Short name
  anti- MGP antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- MGP (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7060
• Gene
  MGP
• Long gene name
  matrix Gla protein
• GenBank acession
  • M58549
• Locus
  12p12.3
• Discovery year
  1991-08-01
• Entrez gene record
  4256
• Pubmed identfication
  • 2394711
• RefSeq identity
  • NM_000900
• Classification
  • Gla domain containing
• VEGA ID
  OTTHUMG00000168740

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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