Soluble CD23 Recombinant Protein

• Catalog number
  40-315
• Price
  Please ask
• Size
  0.005 mg, 0.02 mg

• About recombinant protein
  CD23, the low affinity receptor for IgE, belongs to the C-type lectin structural family and plays a role in the regulation of IgE synthesis and IgE mediated activities. It is found both as a transmembrane receptor protein and in a soluble form, which is generated by proteolytic cleavage of membrane bound CD23. The predominant soluble form of CD23 (sCD23) consists of 172 amino acids corresponding to the extracellular domain of the full length precursor. sCD23, in addition to binding IgE, also exerts a number of IgE independent activities, such as promoting the activation and differentiation of B-cells and stimulating the release of pro-inflammatory cytokines from monocytes. Recombinant human sCD23 is a 19.2 kDa non-glycosylated protein containing 172 amino-acid residues.
• Other name of the recombinant
  CD23, FCE2, CD23A, IGEBF, CLEC4J, BLAST-2, Low affinity immunoglobulin epsilon Fc receptor
• Recombinant in
  E. coli
• SEQUENCE
  MELQVSSGFV CNTCPEKWIN FQRKCYYFGK GTKQWVHARY ACDDMEGQLV SIHSPEEQDF LTKHASHTGS WIGLRNLDLK GEFIWVDGSH VDYSNWAPGE PTSRSQGEDC VMMRGSGRWN DAFCDRKLGA WVCDRLATCT PPASEGSAES MGPDSRPDPD GRLPTPSAPL HS
• Keep at
  The lyophilized Soluble CD23 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Soluble CD23 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Soluble CD23 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  334085203
• Accession nr
  NP_001207429.1
• Pureity
  Greater than 96% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  2208
• Gene name
  Fc fragment of IgE, low affinity II, receptor for (CD23)
• Source
  Homo sapiens
• Uniprot
  P06734
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Soluble   CD23   Protein  
• Gene symbol
  FCER2
• Short name
  Soluble CD23 Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Soluble CD23 Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:3612
• Gene
  FCER2
• Long gene name
  Fc fragment of IgE receptor II
• Synonyms gene
  • CD23A
  • FCE2
• Synonyms gene name
  • Fc fragment of IgE, low affinity II, receptor for (CD23A)
  • Fc fragment of IgE, low affinity II, receptor for (CD23)
• Synonyms
  • CLEC4J
  • CD23
• Synonyms name
  • Fc epsilon receptor II
• GenBank acession
  • M15059
• Locus
  19p13.2
• Discovery year
  1988-08-05
• Entrez gene record
  2208
• RefSeq identity
  • NM_002002
• Classification
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000182517

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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