AZD-4547
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Catalog number9403-5
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PricePlease ask
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Size5 mg
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Alternative_nameN-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide
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DescriptionAZD-4547 is a novel and selective inhibitor of the FGFR1, 2, and 3 tyrosine kinases. It binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and thus resulting in the inhibition of tumor cell proliferation and tumor cell death.
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CAS Number1035270-39-3
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₆H₃₃N₅O₃
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Molecular Weight463.57
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>80 mg/ml)
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HandlingProtect from air and light
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Tag LineA selective inhibitor of the FGFR1, 2, and 3 tyrosine kinases
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID51039095
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SMILESCC1CN(CC(N1)C)C2=CC=C(C=C2)C(=O)NC3=NNC(=C3)CCC4=CC(=CC(=C4)OC)OC
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InChiInChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21(29-30-25)8-5-19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,(H2,28,29,30,32)/t17-,18+
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InChi KeyVRQMAABPASPXMW-HDICACEKSA-N
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MSDS AvailableYes
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Gene target
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Short nameAZD-4547
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Alternative nameAZD-4547
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