AZD-4547

  • Catalog number
    9403-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide
  • Description
    AZD-4547 is a novel and selective inhibitor of the FGFR1, 2, and 3 tyrosine kinases. It binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and thus resulting in the inhibition of tumor cell proliferation and tumor cell death.
  • CAS Number
    1035270-39-3
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₆H₃₃N₅O₃
  • Molecular Weight
    463.57
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>80 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A selective inhibitor of the FGFR1, 2, and 3 tyrosine kinases
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    51039095
  • SMILES
    CC1CN(CC(N1)C)C2=CC=C(C=C2)C(=O)NC3=NNC(=C3)CCC4=CC(=CC(=C4)OC)OC
  • InChi
    InChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21(29-30-25)8-5-19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,(H2,28,29,30,32)/t17-,18+
  • InChi Key
    VRQMAABPASPXMW-HDICACEKSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    AZD-4547
  • Alternative name
    AZD-4547
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