UNC5B:Fc, Recombinant, Human (Netrin Receptor UNC5B, UNC5H2, Protein Unc-5 Homolog 2, Protein Unc-5 Homolog B, p53-regulated Receptor for Death and Life Protein 1)[UNC5B:Fc]

• Catalog number
  MBS635624
• Price
  Please ask
• Size
  NA

• Products_type
  Recombinant Protein
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  UNC5B   Netrin   Receptor   UNC5B   UNC5H2   Protein   Unc-5   Homolog   Protein   Unc-5   Homolog   p53-regulated   Receptor   for   Death   Life   Protein   [UNC5B   Fc]  
• Gene symbol
  UNC5B, UNC5B-AS1
• Short name
  UNC5B:Fc, Recombinant, (Netrin Receptor UNC5B, UNC5H2, Protein Unc-5 Homolog 2, Protein Unc-5 Homolog B, p53-regulated Receptor for Death Life Protein 1)[UNC5B:Fc]
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  Human, HEK 293 cells
• Species
  Human, Humans
• Alternative name
  unc-5 homolog B (C. elegans):fragment c, Rec., H. sapiens (Netrin Receptor unc-5 homolog B (C. elegans), UNC5H2, Protein Unc-5 Homolog 2, Protein Unc-5 Homolog B, p53-regulated Receptor to measure Death and Life Protein 1)[unc-5 homolog B (C. elegans):fragment c]
• Alternative technique
  rec
• Alternative to gene target
  unc-5 homolog B (C. elegans), UNC5B and IDBG-77562 and ENSG00000107731 and 219699, protein binding, Plasma membranes, Unc5b and IDBG-154989 and ENSMUSG00000020099 and 107449, UNC5B and IDBG-629823 and ENSBTAG00000014270 and 100851524,524942

Gene info

• Identity
  HGNC:12568
• Gene
  UNC5B
• Long gene name
  unc-5 netrin receptor B
• Synonyms gene name
  • unc5 (C.elegans homolog) b
  • unc-5 homolog B (C. elegans)
• Synonyms
  • UNC5H2
  • p53RDL1
• GenBank acession
  • AB096256
• Locus
  10q22.1
• Discovery year
  1998-12-09
• Entrez gene record
  219699
• Pubmed identfication
  • 12655055
  • 20693423
• RefSeq identity
  • NM_170744
• Classification
  • Ig-like cell adhesion molecule family
  • I-set domain containing
• VEGA ID
  OTTHUMG00000018422

Gene info

• Identity
  HGNC:45096
• Gene
  UNC5B-AS1
• Long gene name
  UNC5B antisense RNA 1
• Synonyms
  • UASR1
• Locus
  10q22.1
• Discovery year
  2013-02-14
• Entrez gene record
  728978
• Pubmed identfication
  • 30805847
  • 31205563
• RefSeq identity
  • NR_038453
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000018423

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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