Human Tumor necrosis factor ligand superfamily member 10 (TNFSF10)

• Catalog number
  CSB-EP023985HU-200ug
• Price
  Please ask
• Size
  200ug

• Description
  Recombinant Human Tumor necrosis factor ligand superfamily member 10(TNFSF10) ,partial expressed in E.coli
• Specifications
  Uniprot ID: P50591; Host: Homo sapiens (Human); Expression system: E.coli; Expression region: 39-281aa; Sequence information: Extracellular Domain; Tag: N-terminal 6xHis-tagged; Purity: Greater than 90% as determined by SDS-PAGE.
• Additional_information
  MW: 32.4 kDa; Buffer composition: Tris-based buffer with 50% glycerol.
• Storage_and_shipping
  Shipped on ice packs (+4°C). The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. Repeated freezing and thawing should be avoided. Store working aliquots at 4°C for up to one week.
• Notes
  For research use only.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  Tumor   necrosis   factor   ligand   superfamily   member   TNFSF10  
• Gene symbol
  TNFSF10
• Short name
  Tumor necrosis factor ligand superfamily member 10 (TNFSF10)
• Species
  Human, Humans
• Alternative name
  H. sapiens Tumor necrosis factor ligand supergroup member 10 (tumor necrosis factor (ligand) superfamily, member 10)
• Alternative to gene target
  tumor necrosis factor (ligand) superfamily, member 10, Apo-2L and APO2L and CD253 and TL2 and TRAIL, TNFSF10 and IDBG-65161 and ENSG00000121858 and 8743, metal ion binding, Extracellular, Tnfsf10 and IDBG-134362 and ENSMUSG00000039304 and 22035, BT.20790 and IDBG-636176 and ENSBTAG00000018994 and 507215
• Tissue
  tumor

Gene info

• Identity
  HGNC:11925
• Gene
  TNFSF10
• Long gene name
  TNF superfamily member 10
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 10
• Synonyms
  • TRAIL
  • Apo-2L
  • TL2
  • CD253
• GenBank acession
  • U37518
• Locus
  3q26
• Discovery year
  1998-12-04
• Pubmed identfication
  • 8777713
  • 8663110
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000156917

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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