CRT0066101

• Catalog number
  B1847-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochloride
• Description
  CRT0066101 is a potent inhibitor of protein kinase D (PKD). It inhibits all PKD isoforms (IC₅₀ values are 1, 2 and 2.5 nM for PKD1, PKD3 and PKD2 respectively). It displays selectivity for PKD against a panel of >90 protein kinases, including PKCα, MEK, ERK, c-Raf and c-Src.
• CAS Number
  1883545-60-5
• Structure Available
  Yes
• Molecular Formula
  C₁₈H₂₂N₆O.2HCl
• Molecular Weight
  411.33
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent protein kinase D (PKD) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  126970672
• PubChem CID Link
• SMILES
  CCC(CNC1=CC=NC(=C2C=C(C=CC2=O)C3=CN(N=C3)C)N1)N.Cl.Cl
• InChi
  InChI=1S/C18H22N6O.2ClH/c1-3-14(19)10-21-17-6-7-20-18(23-17)15-8-12(4-5-16(15)25)13-9-22-24(2)11-13;;/h4-9,11,14,21,23H,3,10,19H2,1-2H3;2*1H/b18-15+;;/t14-;;/m1../s1
• InChi Key
  YABREXUEJVISSM-ILDIYEGTSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  CRT0066101  
• Short name
  CRT0066101
• Alternative name
  CRT0066101

Similar products