Factor VIII Antibody, ALEXA FLUOR 488

• Catalog number
  bs-2974R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  Factor VIII Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-Factor VIII PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Factor VIII
• Specificity
  This is a highly specific antibody against Factor VIII.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  80-130/2351
• Subcellular location
  Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Factor VIII
• Gene ID Number
  2157
• Swiss Prot
  P00451
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  AHF; F8B; F8C; HEMA; FVIII; DXS1253E; Coagulation factor VIII; Antihemophilic factor; Procoagulant component; F8
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-Factor VIII has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• French translation
  anticorps

• Gene target
  Factor   VIII  
• Gene symbol
  COX8A, G3BP1, MARCHF8
• Short name
  Anti-Factor VIII
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  Factor VIII Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2294
• Gene
  COX8A
• Long gene name
  cytochrome c oxidase subunit 8A
• Synonyms gene
  • COX8
• Synonyms gene name
  • cytochrome c oxidase subunit VIII
  • cytochrome c oxidase subunit VIIIA (ubiquitous)
• Synonyms
  • COX8-2
  • COX8L
  • VIII-L
  • COX
  • VIII
• GenBank acession
  • J04823
• Locus
  11q13.1
• Discovery year
  1989-06-30
• Entrez gene record
  1351
• Pubmed identfication
  • 2543673
  • 2847943
  • 26685157
• RefSeq identity
  • NM_004074
• Classification
  • Mitochondrial complex IV: cytochrome c oxidase subunits
• VEGA ID
  OTTHUMG00000167785

Gene info

• Identity
  HGNC:30292
• Gene
  G3BP1
• Long gene name
  G3BP stress granule assembly factor 1
• Synonyms gene name
  • GTPase activating protein (SH3 domain) binding protein 1
• Synonyms
  • HDH-VIII
  • G3BP
• Synonyms name
  • Ras-GTPase-activating protein SH3-domain-binding protein
  • DNA helicase VIII
• GenBank acession
  • BC006997
• Locus
  5q33.1
• Discovery year
  2006-10-25
• Entrez gene record
  10146
• Pubmed identfication
  • 8649363
  • 9889278
  • 25229650
• RefSeq identity
  • NM_005754
• Classification
  • RNA binding motif containing
  • Endoribonucleases
• VEGA ID
  OTTHUMG00000130123

Gene info

• Identity
  HGNC:23356
• Gene
  MARCHF8
• Long gene name
  membrane associated ring-CH-type finger 8
• Synonyms gene
  • MIR
  • MARCH8
• Synonyms gene name
  • c-mir, cellular modulator of immune recognition
  • membrane-associated ring finger (C3HC4) 8
  • membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
• Synonyms
  • c-MIR
  • CMIR
  • MARCH-VIII
  • RNF178
• GenBank acession
  • AL833316
• Locus
  10q11.21-q11.22
• Discovery year
  2003-11-12
• Entrez gene record
  220972
• Pubmed identfication
  • 12582153
  • 14722266
• RefSeq identity
  • NM_145021
• Classification
  • Ring finger proteins
  • Membrane associated ring-CH-type fingers
• VEGA ID
  OTTHUMG00000019345

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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