CD147/ EMMPRIN/ Neurothelin
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Catalog number
GEN438269
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Price
Please ask
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Size
100ug
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Also known as
CD147
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Other names
basigin isoform 1; Basigin; basigin; CD147 antigen; OK blood group antigen; collagenase stimulatory factor; leukocyte activation antigen M6; extracellular matrix metalloproteinase inducer; tumor cell-derived collagenase stimulatory factor; basigin (Ok blood group); 5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF; CD_antigen: CD147
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Category
Antibodies
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Subcategory
Mnoclonal antibodies
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Gene name
BSG
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Gene name synonims
N/A
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Other gene names
BSG; BSG; M6; OK; 5F7; TCSF; CD147; EMMPRIN; EMMPRIN; TCSF
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Clonality
Monoclonal
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Immunoglobulin isotype
IgG1
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Clone
8D6
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Host organism
Mouse (Mus musculus)
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Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivity
This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification method
N/A
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Form Appearance
N/A
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Concentration
N/A
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Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
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Tested applications
Inhibits Homotypic Aggregation, Adhesion to Matrix Proteins, Migation through Matrigel, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB), Immunohistology (IH)
Gene info
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Identity
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Gene
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Long gene name
basigin (Ok blood group)
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Synonyms gene
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Synonyms gene name
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1993-10-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Basigin family
- I-set domain containing
- Blood group antigens
- CD molecules
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VEGA ID
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Locus Specific Databases
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