Tal1 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-9428R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  Tal1 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-Tal1 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Tal1
• Specificity
  This is a highly specific antibody against Tal1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Tal1
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIalpha, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  bHLHa17; Class A basic helix-loop-helix protein 17; SCL antibody; Stem cell protein; T cell acute lymphocytic leukemia 1; T cell acute lymphocytic leukemia 1 protein; T cell leukemia/lymphoma 5 protein; T-cell acute lymphocytic leukemia protein 1; T-cell leukemia/lymphoma protein 5; Tal 1; Tal 1 product; TAL 1 protein; TAL-1; tal1; TAL1_HUMAN; TCL 5; TCL5.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-Tal1 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  Tal1  
• Gene symbol
  STIL, TAL1
• Short name
  Anti-Tal1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  Tal1 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  T-cell acute lymphocytic leukemia 1, bHLHa17 and SCL and tal-1 and TCL5, TAL1 and IDBG-98262 and ENSG00000162367 and 6886, E-box binding, nuclei, Tal1 and IDBG-175763 and ENSMUSG00000028717 and 21349, TAL1 and IDBG-639733 and ENSBTAG00000005029 and 518657

Gene info

• Identity
  HGNC:10879
• Gene
  STIL
• Long gene name
  STIL centriolar assembly protein
• Synonyms gene
  • SIL
• Synonyms gene name
  • TAL1 (SCL) interrupting locus
  • SCL/TAL1 interrupting locus
• Synonyms
  • MCPH7
• GenBank acession
  • M74558
• Locus
  1p33
• Discovery year
  1997-11-05
• Entrez gene record
  6491
• Pubmed identfication
  • 1922059
  • 2209547
• RefSeq identity
  • NM_003035
• VEGA ID
  OTTHUMG00000007851

Gene info

• Identity
  HGNC:11556
• Gene
  TAL1
• Long gene name
  TAL bHLH transcription factor 1, erythroid differentiation factor
• Synonyms gene
  • TCL5
• Synonyms gene name
  • T-cell acute lymphocytic leukemia 1
• Synonyms
  • SCL
  • bHLHa17
• GenBank acession
  • M29038
• Locus
  1p33
• Discovery year
  1989-05-31
• Entrez gene record
  6886
• Pubmed identfication
  • 2740341
• RefSeq identity
  • NM_003189
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000007847

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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