ETS1 associated protein II Antibody

  • Catalog number
    bs-5164R
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    ETS1 associated protein II Antibody
  • Also known as
    ETS1 associated protein II Antibody
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Target Antigen
    ETS1 associated protein II
  • Specificity
    This is a highly specific antibody against ETS1 associated protein II.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ETS1 associated protein II/EAPII
  • Tested Applications
    WB, IHC-P, IF(IHC-P)
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    EAP 2; EAP II; EAP2; EAPII; ETS 1 associated protein 2; ETS 1 associated protein II; ETS1 associated protein 2; ETS1-associated protein 2; ETS1-associated protein II; tdp2; TRAF and TNF receptor associated protein; TRAF and TNF receptor-associated protein; TTRAP; TYDP2_HUMAN; Tyr DNA phosphodiesterase 2; Tyr-DNA phosphodiesterase 2; Tyrosyl DNA phosphodiesterase 2; Tyrosyl-DNA phosphodiesterase 2; 5''-Tyr-DNA phosphodiesterase; 5''-tyrosyl-DNA phosphodiesterase; AD 022; AD022; MGC111021; MGC9099.
  • Properties
    If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    ETS1-AS1, ETS1
  • Short name
    Anti-ETS1 associated protein II
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Isotype
    Immunoglobulin G (IgG)
  • Alternative name
    ETS1 associated protein II Antibody
  • Alternative technique
    antibodies
  • Alternative to gene target
    v-ets erythroblastosis virus E26 oncogene homolog 1 (avian), ETS-1 and EWSR2 and p54, ETS1 and IDBG-75897 and ENSG00000134954 and 2113, sequence-specific DNA binding, nuclei, Ets1 and IDBG-147548 and ENSMUSG00000032035 and 23871, ETS1 and IDBG-642787 and ENSBTAG00000002341 and 540313
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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