Fosaprepitant

• Catalog number
  9529-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  P-[3-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonic Acid; L 758298
• Description
  Fosaprepitant is a prodrug of Aprepitant (Cat. No. 9531) that acts as a selective, high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. After biologically activated to Aprepitant, it acts as an antiemetic agent.
• CAS Number
  172673-20-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₂₂F₇N₄O₆P
• Molecular Weight
  614.41
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A prodrug of Aprepitant that acts as a selective, high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  219090
• PubChem CID Link
• SMILES
  CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F
• InChi
  InChI=1S/C23H22F7N4O6P/c1-12(14-8-15(22(25,26)27)10-16(9-14)23(28,29)30)40-20-19(13-2-4-17(24)5-3-13)33(6-7-39-20)11-18-31-21(35)34(32-18)41(36,37)38/h2-5,8-10,12,19-20H,6-7,11H2,1H3,(H,31,32,35)(H2,36,37,38)/t12-,19+,20-/m1/s1
• InChi Key
  BARDROPHSZEBKC-OITMNORJSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Fosaprepitant  
• Short name
  Fosaprepitant
• Alternative name
  Fosaprepitant

Product images

Similar products