FNDC3B Antibody, ALEXA FLUOR 488

• Catalog number
  bs-8487R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  FNDC3B Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-FNDC3B PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  FNDC3B
• Specificity
  This is a highly specific antibody against FNDC3B.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FNDC3B
• Gene ID Number
  64778
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Adipogenesis, the process of transforming pre-adipocytes into mature fat cells, is of particular interest due to the role adipocytes play in obesity and type II diabetes. Adipocytes have been shown to affect a variety of functions, including hemostasis, angiogenesis and energy balance, by secreting hormones and bioactive peptides. The FNDC3B protein, also designated FAD104 (factor for adipocyte differentiation 104) or HCV NS5A-binding protein 37, is expressed during early adipogenesis. Belonging to the FNDC3 family of proteins, FNDC3B is a 1,204 amino acid protein that contains nine fibronectin type-III domains. FNDC3B-deficient mice die within one day of birth, suggesting that FNDC3B is crucial for postpartum survival. Mouse embryonic fibroblasts (MEFs) with loss of FNDC3B function displayed a reduction in stress fiber formation, indicating a role for FNDC3B in cell proliferation, adhesion, spreading and migration.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  Factor for adipocyte dferentiation 104; FAD104; fibronectin type III domain containing 3B; FLJ23399; HCV NS5A binding protein 37; NS5ABP37; YVTM2421; MGC10002; PRO4979; DKFZp686D14170; DKFZp762K137; FND3B_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-FNDC3B has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  FNDC3B  
• Gene symbol
  FNDC3B
• Short name
  Anti-FNDC3B
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  FNDC3B Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  fibronectin type III domain containing 3B, FNDC3B and IDBG-65077 and ENSG00000075420 and 101928615,102724045,64778, poly(A) RNA binding, Plasma membranes, Fndc3b and IDBG-134425 and ENSMUSG00000039286 and 72007, FNDC3B and IDBG-636213 and ENSBTAG00000019376 and 615534

Gene info

• Identity
  HGNC:24670
• Gene
  FNDC3B
• Long gene name
  fibronectin type III domain containing 3B
• Synonyms
  • FAD104
  • DKFZp762K137
  • FLJ23399
  • PRO4979
  • YVTM2421
• GenBank acession
  • AF543840
• Locus
  3q26.31
• Discovery year
  2005-01-20
• Entrez gene record
  64778
• Pubmed identfication
  • 15527760
• RefSeq identity
  • NM_022763
• Classification
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000156761

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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