OAC1
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Catalog numberB1079-25
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PricePlease ask
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Size25 mg
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Alternative_nameN-(1H-pyrrolo[2,3-c]pyridin-5-yl)benzamide
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DescriptionOAC1 is an Oct4-activating compound that activates expression through the Oct4 gene promoter. In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC1 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts. OAC1 also upregulates mRNA expression of Oct-4, Sox-2 and Nanog, as well as Tet1.
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CAS Number300586-90-7
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₄H₁₁N₃O
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Molecular Weight237.26
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>30 mg/ml) or EtOH (>20 mg/ml)
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HandlingProtect from air and light
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Tag LineAn Oct-4 activator
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID789882
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SMILESC1=CC=C(C=C1)C(=O)NC2=NC=C3C(=C2)C=CN3
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InChiInChI=1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18)
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InChi KeyHWJRIFZDXJKJJN-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameOAC1
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Alternative nameOAC1
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