Lonafarnib

• Catalog number
  B1616-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  Sarasar; SCH 66336; SCH66336; SCH-66336, 4-(2-(4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-yl)-1-piperidinyl)-2-oxoethyl)-1-piperidinecarboxamide; farnesyltransferase inhibitor; FTI inhibitor
• Description
  Lonafarnib (SCH 66336) is a selectively farnesyltransferase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.
• CAS Number
  193275-84-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₇H₃₁Br₂ClN₄O₂
• Molecular Weight
  638.82
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO (127 mg/mL, 198.8 mM)
• Handling
  Protect from air and light
• Tag Line
  A selective farnesyltransferase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD06795138
• PubChem CID
  148195
• PubChem CID Link
• SMILES
  C1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C(C=C(C=C4CCC5=CC(=CN=C35)Br)Cl)Br)C(=O)N
• InChi
  1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11H2,(H2,31,36)/t25-/m1/s1
• InChi Key
  DHMTURDWPRKSOA-RUZDIDTESA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Lonafarnib  
• Short name
  Lonafarnib
• Alternative name
  Lonafarnib

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