JNK1/2, c-Jun N-terminal Kinase
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Catalog number
AS16 4011
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Price
Please ask
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Size
100 µg
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Available ordering format
Liquid
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Immunogen
Recombinant human c-Src expressed in E. coli. UniProt: Mouse: Q9ESN9, Human: Q9UPT6, Rat: B0VXR4
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Raised in
Mouse
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Clonality
Monoclonal
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Clone
279Q38, IgG1
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Purification
Protein A/G purified.
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How to reconstitute
See included datasheet or contact our support service
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Storage condition
Store at -20°C.
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Verified applications
Western blotting (WB)
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Connected products
anti-mouse secondary antibodies
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Recommended dilutions for use
0.5-1 µg/ml (WB), optimal concentrations should be determined by serial dilutions.
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Molecular weight expected аpparent
see datasheet
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Verified reactivity
Human, Mouse, Rat
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Possible reactivity
to be determined
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No reactivity
No confirmed exceptions from predicted reactivity known at the moment.
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Supplementary information
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References
To be added when available, antibody released in November 2016.
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Scientific context
JNK is a main mitogen-activated protein kinases in mammals. Because of different mRNA splicing this protein is expressed as ten different isoforms. The most common isoforms are JNK1 and JNK2. JNK is activated by many signals in the cell such as growth factors, inflammatory cytokines, and environmental stress. The JNK pathway regulates the cell cycle, apoptotic and transcriptional responses to stress. Alternative names: Stress Activated Protein Kinase (SAPK)
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Notes
This antibody binds to both JNK1 and JNK2 proteins of Mr=46 and 54 kDa.Full activation of JNK needs phosphorylation of a threonine and a tyrosine residue in the motif Thr-Pro-Tyr.
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Protein number
Q9ESN9!!AIR8!!Q9UPT6!!AIR8!!B0VXR4
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TAIR number
Refer to NCBI
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Gene target
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Gene symbol
MAPK8
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Short name
JNK1/2, c-Jun N-terminal Kinase
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Alternative name
JNK1/2, c-jun proto-oncogene N-terminal phosphorylation catalyst
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Alternative to gene target
jun proto-oncogene, AP-1 and AP1 and c-Jun, JUN and IDBG-99221 and ENSG00000177606 and 3725, HMG box domain binding, nuclei, Jun and IDBG-164161 and ENSMUSG00000052684 and 16476, JUN and IDBG-638846 and ENSBTAG00000004037 and 280831
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Gene info
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