-
Alternative_name
1α, 25-Dihydroxycholecalciferol; 1a,25-Dihydroxyvitamin D3; 25-(OH)2-D3
-
Description
An active metabolite of vitamin D3 that activates the vitamin D receptor (VDR). Plays important role in regulating body levels of calcium and phosphorus, and in mineralization of bone. It has widespread effects on cellular differentiation and proliferation, and can modulate immune responsiveness, and central nervous system function. Known to act as a chemopreventive agent against several malignancies including cancers of the prostate and colon and shows synergy with other anticancer compounds.
-
CAS Number
32222-06-3
-
Structure Available
Yes
-
Salt Form
No
-
Molecular Formula
C₂₇H₄₄O₃
-
Molecular Weight
416.64
-
Cell Permeable
No
-
Purity
≥99% by HPLC
-
Solubilities
DMSO (50 mg/ml) or EtOH
-
Handling
Protect from air and light
-
Tag Line
An activator of the vitamin D receptor (VDR)
-
Storage Condition
-20°C
-
Shipping Condition
gel pack
-
Shelf Life
36 months
-
MDL Number
MFCD00867079
-
PubChem CID
5280453
-
-
SMILES
CC(CCCC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
-
InChi
InChI=1S/C27H44O3/c1-18(8-6-14-26(3,4)30)23-12-13-24-20(9-7-15-27(23, 24)5)10-11-21-16-22(28)17-25(29)19(21)2/h10-11,18,22-25,28-30H,2,6-9,12-17H2,1,3-5H3/b20-10+,21-11-/t18-,22-,23-,24+,25+,27-/m1/s1
-
InChi Key
GMRQFYUYWCNGIN-NKMMMXOESA-N
-
-
MSDS Available
Yes