OSI-930
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Catalog numberB1712-5
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PricePlease ask
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Size5 mg
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Alternative_nameOSI-930; OSI930; OSI 930; 3-((quinolin-4-ylmethyl)amino)-N-(4-(trifluoromethoxy)phenyl)thiophene-2-carboxamide
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DescriptionOSI-930 is a potent inhibitor of receptor tyrosine kinases with IC50 values of 80 nM, 9 nM, 8 nM, 15 nM, 41 nM and 22 nM for c-Kit, KDR, Flt, CSF-1R, c-Raf and Lck respectively.
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CAS Number728033-96-3
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₂H₁₆F₃N₃O₂S
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Molecular Weight443.44
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Cell PermeableYes
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Purity>98%
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA Kit, KDR, Flt, CSF-1R, c-Raf and Lck Inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberNA
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PubChem CID9868037
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SMILESC1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F
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InChiInChI=1S/C22H16F3N3O2S/c23-22(24,25)30-16-7-5-15(6-8-16)28-21(29)20-19(10-12-31-20)27-13-14-9-11-26-18-4-2-1-3-17(14)18/h1-12,27H,13H2,(H,28,29)
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InChi KeyFGTCROZDHDSNIO-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameOSI-930
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Alternative nameOSI-930
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