anti- PDCD6IP antibody

• Catalog number
  FNab06243
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.
• Immunogen
  programmed cell death 6 interacting protein
• Synonyms
  AIP1, ALG 2 interacting protein 1, Alix, DRIP4, HP95, KIAA1375, PDCD6 interacting protein, PDCD6IP
• Calculated MW
  109 kDa
• Uniprot ID
  Q8WUM4
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Image4
  Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06243( PDCD6IP antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PDCD6IP  
• Gene symbol
  PDCD6IP-DT, PDCD6IP
• Short name
  anti- PDCD6IP antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- programmed cellular death 6 interacting protein (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  programmed cell death 6 interacting protein, AIP1 and ALIX and DRIP4 and HP95, PDCD6IP and IDBG-24373 and ENSG00000170248 and 10015, calcium-dependent protein binding, Cell surfaces, Pdcd6ip and IDBG-203055 and ENSMUSG00000032504 and 18571, PDCD6IP and IDBG-644175 and ENSBTAG00000017426 and 533406

Gene info

• Identity
  HGNC:55244
• Gene
  PDCD6IP-DT
• Long gene name
  PDCD6IP divergent transcript
• Locus
  3p22.3
• Discovery year
  2020-09-17
• Entrez gene record
  105377023
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:8766
• Gene
  PDCD6IP
• Long gene name
  programmed cell death 6 interacting protein
• Synonyms gene name
  • programmed cell death 6-interacting protein
• Synonyms
  • Alix
  • AIP1
  • Hp95
• Synonyms name
  • ALG-2 interacting protein X
• GenBank acession
  • BC020066
• Locus
  3p22.3
• Discovery year
  1999-12-10
• Entrez gene record
  10015
• Pubmed identfication
  • 9880530
• VEGA ID
  OTTHUMG00000130751

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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