Sheep Polyclonal (IgG) to Human Fibrinogen

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Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
About

Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Group

Polyclonals and antibodies

Gene target

Fibrinogen
Gene symbol

FGG, FGB, FGA
Short name

Polyclonal (IgG) Fibrinogen
Technique

Polyclonal, IgG, IgGs, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
Host

Sheep
Isotype

IgG, IgG
Species

Human, Humans, The sheep (Ovis aries) ELISAs are detecting sheep proteins and antigens. Some epitopes will also recognize goat proteins. Sheep and goats are also used to produce polyclonals. An adult female sheep is referred to as a ewe a male as a ram, a castrated male as a wether, and a younger sheep as a lamb. Sheeps
Alternative name

ovine polyclonal (Immunoglobulin G) to H. sapiens Fibrinogen
Alternative technique

polyclonals, immunoglobulins

Identity

HGNC:3694
Gene

FGG
Long gene name

fibrinogen gamma chain
Synonyms gene name
- fibrinogen, gamma polypeptide
Locus

4q32.1
Discovery year

2001-06-22
Entrez gene record

2266
RefSeq identity
- NM_021870
Classification
- Fibrinogen C domain containing
- Receptor ligands
VEGA ID

OTTHUMG00000150329
Locus Specific Databases
- LOVD EAHAD Coagulation Factor Variant Database
- LRG_585