Human CellExp™ BTN1A1 / Butyrophilin, Human Recombinant

• Catalog number
  P1261-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  BTN1A1, Butyrophilin, BTN
• Alternative_names
  BTN1A1, Butyrophilin, BTN
• Description
  Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
• Recombinant
  Yes
• Source
  HEK293 cells
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per/ug
• Molecular Weight
  25.8 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in sterile deionized water.
• Background Information
  Butyrophilin subfamily 1 member A1 (BTN1A1) is also known as BTN, which is a member of the immunoglobulin superfamily and the major protein, associated with fat droplets in the milk. BTN1A1 may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. Furthermore, BTN1A1 regulates the amount of lipids and size of droplets expressed in milk and inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   BTN1A1   Butyrophilin  
• Gene symbol
  BTN1A1
• Short name
  CellExp™ BTN1A1 / Butyrophilin, Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ BTN1A1 / Butyrophilin, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:1135
• Gene
  BTN1A1
• Long gene name
  butyrophilin subfamily 1 member A1
• Synonyms gene
  • BTN
• Synonyms gene name
  • butyrophilin, subfamily 1, member A1
• Synonyms
  • BT
  • BTN1
• GenBank acession
  • U39576
• Locus
  6p22.2
• Discovery year
  1995-07-11
• Entrez gene record
  696
• Pubmed identfication
  • 8114113
  • 9382921
• RefSeq identity
  • NM_001732
• Classification
  • Butyrophilins
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000016358

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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