Masitinib

• Catalog number
  2007-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  AB-1010
• Description
  Cell-permeable. A protein tyrosine kinase (PTK) inhibitor.  targeting KIT that is active, orally bioavailable in vivo, and has low toxicity. Masitinib also potently inhibited recombinant PDGFR and the intracellular kinase Lyn, and to a lesser extent, fibroblast growth factor receptor 3. In contrast, masitinib demonstrated weak inhibition of ABL and c-Fms and was inactive against a variety of other tyrosine and serine/threonine kinases.
• CAS Number
  790299-79-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₈H₃₀N₆OS
• Molecular Weight
  498.64
• Cell Permeable
  Yes
• Purity
  ≥99% by HPLC
• Solubilities
  DMSO (>100 mg/ml) or EtOH (4 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent c-KIT, PDGF and FGFR nhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24months
• MDL Number
  MFCD09954132
• PubChem CID
  10074640
• PubChem CID Link
• SMILES
  CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC(=CS4)C5=CN=CC=C5
• InChi
  InChI=1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3- 11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11, 16-17,19H,12-15,18H2,1-2H3,(H,30,35)(H,31,32)
• InChi Key
  WJEOLQLKVOPQFV-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Masitinib  
• Short name
  Masitinib
• Alternative name
  Masitinib

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