Elastase Inhibitor, SPCK
#
-
Catalog number1921-5
-
Price:
-
Size5 mg
-
-
Alternative_nameMeOSuc-Ala-Ala-Pro-Val-chloromethylketone; MeOSuc-AAPV-CMK
-
DescriptionA potent, irreversible inhibitor of human leukocyte elastase (HLE) (Ki = 10 µM).
-
CAS Number65144-34-5
-
Structure AvailableYes
-
Peptide sequenceYes
-
Salt FormNo
-
Molecular FormulaC₂₂H₃₅ClN₄O₇
-
Molecular Weight503
-
Cell PermeableNo
-
Purity≥98% by TLC
-
SolubilitiesDMSO
-
HandlingProtect from air and mositure
-
Tag LineA potent, irreversible human leukocyte elastase (HLE) inhibitor
-
Storage Condition-20°C
-
Shipping Conditiongel pack
-
Shelf Life36 months
-
MDL NumberMFCD00077136
-
PubChem CID5486692
-
SMILESCC(C)C(C(=O)CCl)NC(=O)C1CCCN1C(=O)C(C)NC(=O)C(C)NC(=O)CCC(=O)OC
-
InChiInChI=1S/C22H35ClN4O7/c1-12(2)19(16(28)11-23)26-21(32)15-7-6-10-27(15)22 (33)14(4)25-20(31)13(3)24-17(29)8-9-18(30)34-5/h12-15,19H,6-11H2,1-5H3, (H,24,29)(H,25,31)(H,26,32)/t13-,14-,15-,19-/m0/s1
-
InChi KeyPJGDFLJMBAYGGC-XLPNERPQSA-N
-
MSDS AvailableYes
-
Additional descriptionTissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
-
Gene target
-
Short nameElastase Inhibitor, SPCK
-
Alternative nameElastase suppressor, SPCK
-