Cycloheximide (100 mM)

  • Catalog number
    1041-1
  • Price
    Please ask
  • Size
    1 ml
  • Alternative_name
    3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide, Actidione, Naramycin A
  • Description
    A very active antibiotic against many yeasts and fungi. Inhibits protein synthesis in eukaryotes (but not in prokaryotes) by interfering with the translocation step. It inhibits chain initiation as well as chain elongation by acting on the 60S subunit of the eukaryote ribosome, interacting directly with enzyme translocase. Cycloheximide is used as an inhibitor to study cell-free protein biosynthesis in eukaryotes and also used to block ribosome-dependent in vivo polypeptide synthesis. It induces apoptosis in a variety of cells, but can also delay or inhibit apoptosis by other agents.
  • CAS Number
    66-81-9
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₅H₂₃NO₄
  • Molecular Weight
    281.35
  • Cell Permeable
    Yes
  • Purity
    >95%
  • Handling
    Protect from light and moisture
  • Tag Line
    A protein synthesis inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    6 months
  • MDL Number
    MFCD00082346
  • PubChem CID
    6197
  • SMILES
    CC1CC(C(=O)C(C1)C(CC2CC(=O)NC(=O)C2)O)C
  • InChi
    InChI=1S/C15H23NO4/c1-8-3-9(2)15(20)11(4-8)12(17)5-10-6-13(18)16-14(19) 7-10/h8-12,17H,3-7H2,1-2H3,(H,16,18,19)/t8-,9-,11-,12+/m0/s1
  • InChi Key
    YPHMISFOHDHNIV-FSZOTQKASA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Cycloheximide (100 mM)
  • Alternative name
    Cycloheximide (100 millimeter)
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