Rabbit Anti Human GCGR Antibody-FITC

• Catalog number
  CSB-PA009316LC01HU_100ug
• Price
  Please ask
• Size
  100ug

• Long name
  Rabbit Antibody against Human GCGR, FITC
• Synonym name
  GCGR Human Antibody
• Species reactivity
  Human
• Tested applications recommended dilutions
  ELISA
• Conjugation
  FITC
• Antibody isotype
  IgG
• UniProt ID
  P47871
• Format
  Liquid, diluted in buffer
• Buffer composition
  Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
• Purity
  >95%
• Purification method
  Protein G purified
• Antibody category
  Polyclonal Antibodies
• Immunogen type
  Recombinant Human Glucagon receptor protein (26-136AA)
• Immunogen species
  Human
• Alias
  Glucagon receptorGL-R,GCGR
• Background
  G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
• Clonality
  Polyclonal antibody
• Shipping and storage
  GCGR Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
• Short name of the antigen
  Glucagon receptor
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Cusabio Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Cusabio FITC is highly sensitive to pH extremes. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional conjugation
  Anti-FITC Antibody
• About
  Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

• Gene target
  GCGR  
• Gene symbol
  GCGR
• Short name
  Anti-GCGR
• Technique
  anti human, Antibody, Rabbit, anti, FITC, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, Fluorescein
• Host
  Rabbit, Rabbits
• Label
  FITC
• Species
  Human, Humans
• Alternative name
  GCGR Antibody,FITC conjugated
• Alternative technique
  antibodies, rabbit-anti, fluorescine
• Alternative to gene target
  gluca this GO n receptor, GGR and GL-R, GCGR and IDBG-227533 and ENSG00000215644 and 2642, peptide hormone binding, Plasma membranes, Gcgr and IDBG-214830 and ENSMUSG00000025127 and 14527, BT.27844 and IDBG-642400 and ENSBTAG00000003786 and 515433

Gene info

• Identity
  HGNC:4192
• Gene
  GCGR
• Long gene name
  glucagon receptor
• Synonyms
  • GGR
• GenBank acession
  • U03469
  • L20316
• Locus
  17q25.3
• Discovery year
  1994-03-04
• Entrez gene record
  2642
• Pubmed identfication
  • 8020989
• RefSeq identity
  • NM_000160
• Classification
  • Glucagon receptor family
• VEGA ID
  OTTHUMG00000177914

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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