Eliglustat

• Catalog number
  B1217-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-((1R,2R)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)octanamide hemi((2R,3R)-2,3-dihydroxysuccinate); Genz99067
• Description
  Eliglustat is a potent and specific inhibitor of glucosylceramide synthase. Eliglustat is a new promising substrate reduction therapy (SRT) for Gaucher disease (GD). Eliglustat works by inhibiting UDP-glucosylceramide synthase, the first enzyme that catalyzes the biosynthesis of glycosphingolipids, thus reducing the load of glucosylceramide influx into the lysosome.
• CAS Number
  491833-29-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₃H₃₆N₂O
• Molecular Weight
  404.54
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO(>5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent and specific glucosylceramide synthase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  23652731
• PubChem CID Link
• SMILES
  CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O
• InChi
  InChI=1S/C23H36N2O4/c1-2-3-4-5-6-9-22(26)24-19(17-25-12-7-8-13-25)23(27)18-10-11-20-21(16-18)29-15-14-28-20/h10-11,16,19,23,27H,2-9,12-15,17H2,1H3,(H,24,26)/t19-,23-/m1/s1
• InChi Key
  FJZZPCZKBUKGGU-AUSIDOKSSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Eliglustat  
• Short name
  Eliglustat
• Alternative name
  Eliglustat

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