Human CellExp™ BTN3A1 / CD277, Fc Tag, Human Recombinant

• Catalog number
  P1263-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  BTN3A1, CD277, BTF5
• Alternative_names
  BTN3A1, CD277, BTF5
• Description
  Plays a role in T-cell activation and in the adaptive immune response.
• Recombinant
  Yes
• Source
  HEK293 cells
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 1.0 EU per/ug
• Molecular Weight
  50.8 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized from 0.22 um filtered solution in 50 mM Tris, 100 mM Glycine, pH 7.5. Normally trehalose is added as protectant before lyophilization.
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in sterile deionized water.
• Background Information
  Butyrophilin subfamily 3 member A1 (BTN3A1) is also known as CD277 and BTF5, which belongs to the immunoglobulin superfamily and contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 plays a role in T-cell activation and in the adaptive immune response. Also, BTN3A1 regulates the proliferation of activated T-cells and the release of cytokines and IFNG by activated T-cells. Furthermore, BTN3A1 mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   BTN3A1   CD277   Tag  
• Gene symbol
  BTN3A1
• Short name
  CellExp™ BTN3A1 / CD277, Fc Tag, Recombinant
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  Fc Tag
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ BTN3A1 / CD277, fragment c detection labelled, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:1138
• Gene
  BTN3A1
• Long gene name
  butyrophilin subfamily 3 member A1
• Synonyms gene name
  • butyrophilin, subfamily 3, member A1
• Synonyms
  • BT3.1
  • BTF5
  • CD277
  • BTN3.1
• GenBank acession
  • U90552
• Locus
  6p22.2
• Discovery year
  1999-08-27
• Entrez gene record
  11119
• Pubmed identfication
  • 9149941
• Classification
  • C2-set domain containing
  • V-set domain containing
  • Butyrophilins
  • CD molecules
• VEGA ID
  OTTHUMG00000014449

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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