FITC-Linked Polyclonal Antibody to Suppressors Of Cytokine Signaling 2 (SOCS2)

• Catalog number
  MBS2079363
• Price
  Please ask
• Size
  0,1 mg

• Other size
  please contact us to order other different size
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This MyBioSource Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MyBioSource FITC is highly sensitive to pH extremes.
• Description
  Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. Cell nucleus signaling proteins and molecules are part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, and diabetes. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be created.
• Conjugation
  Anti-FITC Antibody
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  Linked   Suppressors   Cytokine   Signaling   SOCS2  
• Gene symbol
  SOCS2-AS1, SOCS2
• Short name
  FITC-Linked Polyclonal Antibody Suppressors Of Cytokine Signaling 2 (SOCS2)
• Technique
  Polyclonal, Antibody, FITC, antibodies against human proteins, antibodies for, Fluorescein, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  FITC
• Alternative name
  fluorecein-Linked polyclonal (antibody to-) to Suppressors on Cytokine Signaling 2 (suppressor on cytokine signaling 2)
• Alternative technique
  polyclonals, antibodies, fluorescine
• Alternative to gene target
  suppressor of cytokine signaling 2, CIS2 and Cish2 and SOCS-2 and SSI-2 and SSI2 and STATI2, SOCS2 and IDBG-51299 and ENSG00000120833 and 8835, JAK pathway signal transduction adaptor activity, Cytoplasm, SOCS2 and IDBG-630845 and ENSBTAG00000012007 and 338437

Gene info

• Identity
  HGNC:27054
• Gene
  SOCS2-AS1
• Long gene name
  SOCS2 antisense RNA 1
• Synonyms gene name
  • SOCS2 antisense RNA 1 (non-protein coding)
• Locus
  12q22
• Discovery year
  2012-06-30
• Entrez gene record
  144481
• Pubmed identfication
  • 24168098
• RefSeq identity
  • NR_038263
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000170159

Gene info

• Identity
  HGNC:19382
• Gene
  SOCS2
• Long gene name
  suppressor of cytokine signaling 2
• Synonyms
  • STATI2
  • SSI2
  • SOCS-2
  • SSI-2
  • CIS2
  • Cish2
• Synonyms name
  • STAT-induced STAT inhibitor-2
• GenBank acession
  • AF037989
• Locus
  12q
• Discovery year
  2002-11-13
• Entrez gene record
  8835
• Pubmed identfication
  • 9344848
  • 9266833
• Classification
  • Suppressors of cytokine signaling
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000170160

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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