TCTEL1/DYNLT1 Antibody, ALEXA FLUOR 594

• Catalog number
  bs-11310R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  TCTEL1/DYNLT1 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-TCTEL1/DYNLT1 PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  TCTEL1/DYNLT1
• Specificity
  This is a highly specific antibody against TCTEL1/DYNLT1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TCTEL1
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein heavy, intermediate, light and light-intermediate chains are all components of minus end-directed motors; the complex transports cellular cargos towards the central region of the cell. Axonemal Dynein motors contain one to three non-identical heavy chains and cause a sliding of microtubules in the axonemes of cilia and flagella in a mechanism necessary for cilia to beat and propel the cell. Cytoplasmic Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. The carboxy terminus of Dynein is important for microtubule-dependent motility and is highly conserved, while the amino terminal regions are more variable. Tctex1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X?(SCN10A). Tctex1, also designated CW-1 or TCTEL1 is expressed in heart, placenta, skeletal muscle, kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Several proteins regulate Dynein activity, including dynactin, LIS1 and NudEL(NudE-like).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  Dynein light chain Tctex-type 1; Protein CW-1; T-complex testis-specic protein 1 homolog; DYLT1_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  TCTEL1/DYNLT1  
• Gene symbol
  DYNLT1
• Short name
  Anti-TCTEL1/DYNLT1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  TCTEL1/DYNLT1 Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies
• Alternative to gene target
  dynein, light chain, Tctex-type 1, CW-1 and TCTEL1 and tctex-1, DYNLT1 and IDBG-98463 and ENSG00000146425 and 6993, identical protein binding, Cytoplasm, DYNLT1 and IDBG-635357 and ENSBTAG00000004472 and 282380

Gene info

• Identity
  HGNC:11697
• Gene
  DYNLT1
• Long gene name
  dynein light chain Tctex-type 1
• Synonyms gene
  • TCTEL1
• Synonyms gene name
  • t-complex-associated-testis-expressed 1-like 1
• Synonyms
  • Tctex-1
  • TCTEX1
• GenBank acession
  • D50663
• Locus
  6q25.3
• Discovery year
  1996-03-12
• Entrez gene record
  6993
• Pubmed identfication
  • 8646886
  • 16260502
• RefSeq identity
  • NM_006519
• Classification
  • Dynein 2 complex subunits
  • Dynein 1 complex subunits
  • Dyneins, axonemal outer arm complex subunits
• VEGA ID
  OTTHUMG00000015918

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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