Synonyms HAVCR2, TIM3, TIMD3, FLJ14428, KIM3
Alternates names HAVCR2, TIM3, TIMD3, FLJ14428, KIM3
Taglines A Th1-specific cell surface protein that regulates macrophage activation.
NCBI Gene ID #. 84868
NCBI Gene Symbol HAVCR2
Gene Source Human
Accession # Q8TDQ0
Source HEK293 cells
Activity (Specifications/test method) N/A
Biological activity Measured by its binding ability in a functional ELISA. Immobilized rh-Galectin-9 at 500 ng/ml can bind rhKIM3-Fc with an apparent KD
Results Measured by its binding ability in a functional ELISA. Immobilized rh-Galectin-9 at 500 ng/ml can bind rhKIM3-Fc with an apparent KD
Molecular Weight This protein is fused with the Fc region of human IgG1 at the C-terminus and has a calculated MW of 42 kDa after removal of signal peptide. In DTT-reduced SDS-PAGE, rhKIM3-Fc protein migrates as 45 kDa poly peptide due to glycosylation.
Storage Temp. -20°C
Shipping Gel Pack
Shelf Life 1 year
Physical form description Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM glycine, pH 7.0. Normally Mannitol or Trehalose is added as protectants before lyophilization.
Reconstitution Instructions Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.
Handling Centrifuge the vial prior to opening.
Usage For Research Use Only! Not to be used in humans
Properties Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Additional source Recombinants or rec. proteins
Short name CellExp KIM3/HAVCR2, recombinant
Alternative name H. sapiens CellExp KIM3/hepatitis A virus cellular receptor 2, H. sapiens recombinant
Alternative technique rec
Alternative to gene target hepatitis A virus cellular receptor 2, HAVCR2 and IDBG-55271 and ENSG00000135077 and 84868, protein binding, Plasma membranes, Havcr2 and IDBG-165782 and ENSMUSG00000020399 and 171285