gp120 (ADA) (HIV-1/Clade B) (aa 34-518), monomer only

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Gene

The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome(AIDS). AIDS is a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. Infection with HIV occurs by the transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. recombinant HIV 1 and 2 gag gene proteins p24, p17, p55 immunodominant epitopes and envelope glycoproteins, gp120 are used for production of diagnostic detection antibodies.

Gene target

gp120 ADA HIV-1/Clade 34-518 monomer only
Gene symbol

IGHV7-34-1, ADA, SNORD115-34, IGKV3D-34, IGKV3-34, IGHV4-34, IGLV2-34, RNU6-34P, RASSF2, PHF11
Short name

gp120 (ADA) (HIV-1/Clade B) (aa 34-518), monomer only
Alternative name

gp120 (adenosine deaminase) (human immunodeficiency virus-1/Clade B) (aa 34-518), monomer only
Alternative to gene target

adenosine deaminase, ADA and IDBG-76830 and ENSG00000196839 and 100, deaminase activity, Extracellular, Ada and IDBG-211962 and ENSMUSG00000017697 and 11486, ADA and IDBG-642808 and ENSBTAG00000005280 and 280712
Virus

hiv

Identity

HGNC:5664
Gene

IGHV7-34-1
Long gene name

immunoglobulin heavy variable 7-34-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable 7-34-1
- immunoglobulin heavy variable 7-34-1 pseudogene
GenBank acession
- AB019439
Locus

14q32.33
Discovery year

2000-04-04
Entrez gene record

28382
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152085

Identity

HGNC:186
Gene

ADA
Long gene name

adenosine deaminase
Synonyms
- ADA1
GenBank acession
- X02994
Locus

20q13.12
Discovery year

1986-01-01
Entrez gene record

100
Pubmed identfication
- 6198240
- 6090454
RefSeq identity
- NM_000022
Classification
- Adenosine deaminase family
VEGA ID

OTTHUMG00000033081
Locus Specific Databases
- ADAbase: Mutation registry for Adenosine Deaminase Deficiency
- LRG_16

Identity

HGNC:5828
Gene

IGKV3D-34
Long gene name

immunoglobulin kappa variable 3D-34 (pseudogene)
Synonyms gene name
- immunoglobulin kappa variable 3D-34
- immunoglobulin kappa variable 3D-34 pseudogene
GenBank acession
- X71895
Locus

2p11.2
Discovery year

2000-04-18
Entrez gene record

28871
RefSeq identity
- NG_000833
Classification
- Immunoglobulin kappa locus at 2p11.2
VEGA ID

OTTHUMG00000151601

Identity

HGNC:5820
Gene

IGKV3-34
Long gene name

immunoglobulin kappa variable 3-34 (pseudogene)
Synonyms gene name
- immunoglobulin kappa variable 3-34
- immunoglobulin kappa variable 3-34 pseudogene
GenBank acession
- X71891
Locus

2p11.2
Discovery year

2000-04-18
Entrez gene record

28909
RefSeq identity
- NG_000834
Classification
- Immunoglobulin kappa locus at 2p11.2
VEGA ID

OTTHUMG00000151693

Identity

HGNC:5893
Gene

IGLV2-34
Long gene name

immunoglobulin lambda variable 2-34 (pseudogene)
Synonyms gene name
- immunoglobulin lambda variable 2-34
- immunoglobulin lambda variable 2-34 pseudogene
GenBank acession
- D87013
Locus

22q11.22
Discovery year

2000-05-08
Entrez gene record

28810
RefSeq identity
- NG_000002
Classification
- Immunoglobulin lambda locus at 22q11.2
VEGA ID

OTTHUMG00000151174