Anti-HSP70 1A/1B (Polyclonal), ALEXA Fluor 594
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Catalog numberGENTObs-0244R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptideHSP70 1A/1B
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SpecificityThis antibody reacts specifically with HSP70 1A/1B
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ModificationNo modification has been applied to this antibody
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Modification siteNone
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsCytoplasm
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Antigen SourceKLH conjugated synthetic peptide derived from human HSP70 1A/1B
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Gene ID3303
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Swiss ProtP08107
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ApplicationsIF(IHC-P)
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Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
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Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationIn cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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SynonymsHSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A; HEL-S-103; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2; HSPA1A; HSX70
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Also known asHSP70 1A/1B Polyclonal Antibody
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Other nameAnti-HSP70 1A/1B Polyclonal
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Gene target
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Gene symbolHSPA1B, HSPA14, HSPA1A, HSPA1L
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Short nameAnti-HSP70 1A/1B
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TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameHSP70 1A/1B Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniquepolyclonals, antibodies
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Gene info
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Identity
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Gene
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Long gene nameheat shock protein family A (Hsp70) member 1B
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Synonyms gene name
- heat shock 70kD protein 1B
- heat shock 70kDa protein 1B
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Synonyms
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Locus
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Discovery year1995-08-11
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Entrez gene record
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Pubmed identfication
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Classification
- TIM23 complex
- Heat shock 70kDa proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameheat shock protein family A (Hsp70) member 14
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Synonyms gene name
- heat shock 70kDa protein 14
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-04-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Heat shock 70kDa proteins
Gene info
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Identity
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Gene
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Long gene nameheat shock protein family A (Hsp70) member 1A
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Synonyms gene
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Synonyms gene name
- heat shock 70kD protein 1A
- heat shock 70kDa protein 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Classification
- TIM23 complex
- Heat shock 70kDa proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameheat shock protein family A (Hsp70) member 1 like
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Synonyms gene name
- heat shock 70kD protein-like 1
- heat shock 70kDa protein 1-like
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-05-12
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Entrez gene record
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Pubmed identfication
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Classification
- TIM23 complex
- Heat shock 70kDa proteins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data