hydrogen exchanger 3 Antibody, ALEXA FLUOR 647
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Catalog numberbs-8601R-A647
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Price:
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Size100ul
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Long namehydrogen exchanger 3 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
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Also known asAnti-hydrogen exchanger 3 PAb ALEXA FLUOR 647
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 647
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target Antigenhydrogen exchanger 3
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SpecificityThis is a highly specific antibody against hydrogen exchanger 3.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NHE3
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenNHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission650nm/665nm
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SynonymsNa+/H+ exchanger 3; NHE 3; NHE-3; NHE3; SL9A3_HUMAN; SLC9A 3; Sodium; Slc9a3; Sodium/hydrogen exchanger 3; Sodium/hydrogen exchanger, apical epithelial; Solute carrier family 9 sodium/hydrogen exchanger, isoform 3; Solute carrier family 9 sodium/hydrogen exchanger, member 3; Solute carrier family 9 member 3; MGC126718; MGC126720.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-hydrogen exchanger 3 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 647
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French translationanticorps
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Gene target
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Gene symbolSLC9A3P1, SLC9A3R1, SLC9A3R2
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Short nameAnti-hydrogen exchanger 3
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 647
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Alternative namehydrogen exchanger 3 Polyclonal Antibody, ALEXA FLUOR 647
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namesolute carrier family 9 member 3 pseudogene 1
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Synonyms gene
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Synonyms gene name
- solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 pseudogene
- solute carrier family 9 (sodium/hydrogen exchanger), member 3 pseudogene
- solute carrier family 9 (sodium/hydrogen exchanger), member 3 pseudogene 1
- solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 pseudogene 4
- solute carrier family 9 (sodium/hydrogen exchanger), member 3 pseudogene 4
- solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 pseudogene 1
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Locus
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Discovery year1996-03-13
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSLC9A3 regulator 1
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Synonyms gene name
- solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1
- solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 1
- solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
- solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-02-26
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Entrez gene record
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Pubmed identfication
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Classification
- PDZ domain containing
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSLC9A3 regulator 2
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Synonyms gene name
- solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 2
- solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2
- solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
- solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-02-26
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Entrez gene record
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Pubmed identfication
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Classification
- PDZ domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data