TrkB Antibody
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Catalog number3593-100
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Price:
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Size100 µg
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Antibody TargetTrkB
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Target Alternative NameNTRK2 , GP145-TrkB , TRKB , Trk-B , tyrosine receptor kinase
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat, chicken
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Immunogen SequenceSynthetic peptide surrounding amino acid 810 of human TrkB
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AccessionQ63604
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Gene Id25054
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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FormulationIn phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.
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PurificationAffinity purified
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ApplicationWestern blot, Immunoprecipitation, Immunofluorescence
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Application And UsagesWestern blotting (0.5-4 µg/ml), immunofluorescence (5-10 µg/ml). However, the optimal concentrations should be determined individually. Trk protein exists as variably glycosylated entities with the major forms having molecular weights of 140 kDa, 110 kDa, and the unglycosylated form of 80 kDa.
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DescriptionDue to the various splice variants, the trk proteins exist as variably glycosylated entities with the major forms having molecular weights of 140-145 kDa, 110 kDa and the unglycosylated form of 80 kDa. trkB contains 33.3% carbohydrate by weight representing modification on 10 of 12 N-glycosylation sites. The primary ligand for trkB is BDNF which induces the phosphorylation of the protein and subsequent binding of PLC-gamma via SH2 domains. TrkB may function to modulate neuronal responses to the neurotrophins acting throμgh trkB such as BDNF.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolNTRK2
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Short nameTrkB Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameTrkB (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameneurotrophic receptor tyrosine kinase 2
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Synonyms gene name
- neurotrophic tyrosine kinase, receptor, type 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-07-18
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Entrez gene record
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Pubmed identfication
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Classification
- Receptor tyrosine kinases
- I-set domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data