Niclosamide

• Catalog number
  1826-500
• Price
  Please ask
• Size
  500 mg

• Alternative_name
  5-Chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
• Description
  A STAT3 signaling pathway inhibitor. Niclosamide potently inhibits the activation and transcriptional function of STAT3 and induces cell growth inhibition, apoptosis, and cell cycle arrest of cancer cells with constitutively active STAT3. Also reversibly inhibits mTORC1 signaling and stimulates autophagy in vitro; displays antineoplastic effects in acute myelogenous leukemia (AML) stem cells.
• CAS Number
  50-65-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₃H₈Cl₂N₂O₄
• Molecular Weight
  327.12
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (10 mM) or Ethanol (25 mM)
• Handling
  Protect from air and light
• Tag Line
  A STAT3 signaling pathway inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD00057597
• PubChem CID
  4477
• PubChem CID Link
• SMILES
  C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O
• InChi
  InChI=1S/C13H8Cl2N2O4/c14-7-1-4-12(18)9(5-7)13(19)16-11-3-2-8(17(20)21)6-10(11)15/h1-6,18H,(H,16,19)
• InChi Key
  RJMUSRYZPJIFPJ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Niclosamide  
• Short name
  Niclosamide
• Alternative name
  Niclosamide

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