P-glycoprotein Antibody
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Catalog number6970-100
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PricePlease ask
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Size100 µg
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Antibody TargetP-glycoprotein
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Target Alternative NameP-gp, Multidrug resistance protein 1, MDR1, ATP-binding cassette sub-family B (MDR/TAP) member 1, ABCB1
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Antibody TypePolyclonal
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Species ReactivitiesHuman, Mouse, Rat
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Immunogen SequenceSynthetic peptide corresponding to amino acids around position 630 of human P-glycoprotein
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AccessionP08183
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Gene Id5243
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AppearanceSolid
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FormLyophilized
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FormulationEach vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3
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PurificationImmunogen affinity purified antibody
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ApplicationIHC-P, IHC-F
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Positive ControlIHC: Mouse Kidney, Mouse Intestine, Rat Kidney, Human Lung Cancer tissue
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Application And UsagesIHC: 1:500-1:1000 of 0.5 mg/ml stock
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DescriptionP-gp, also called MDR1 or ABCB1, is a glycoprotein that in humans is encoded by the ABCB1 gene. P-gp is a well-characterized ABC-transporter (which transports a wide variety of xenobiotics across extra- and intracellular membranes). It is an ATP-dependent drug efflux pump with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein functions in the kidneys, liver, blood–brain barrier and the intestinal epithelium.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe vial should be centrifuged to collect the lyophilized solid before reconstituting
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Western Blot VerifiedNot Verified
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Immunocytochemistry VerifiedVerified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Dot Blot VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolAPCS, ABCB5, ALG3
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Short nameP-glycoprotein Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit Ig
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Alternative nameP-glycoprotein (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameamyloid P component, serum
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Short pentraxins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameATP binding cassette subfamily B member 5
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Synonyms gene name
- ATP-binding cassette, sub-family B (MDR/TAP), member 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-10-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- ATP binding cassette subfamily B
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameALG3 alpha-1,3- mannosyltransferase
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Synonyms gene name
- asparagine-linked glycosylation 3 homolog (yeast, alpha-1,3-mannosyltransferase)
- asparagine-linked glycosylation 3, alpha-1,3- mannosyltransferase homolog (S. cerevisiae)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-10-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Dolichyl D-mannosyl phosphate dependent mannosyltransferases
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data