Hydroxy Dynasore

  • Catalog number
    B2642-25
  • Price
    Please ask
  • Size
    25 mg
  • Alternative_name
    Dyngo 4a, 3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide
  • Description
    Hydroxy Dynasore is an analog of Dynasore (Cat. No. 1900) that acts as a potent dynamin inhibitor (IC₅₀ values are 0.38 and 2.6 μM for dynamin 1 and 2 respectively). Inhibits dynamin-mediated endocytosis in multiple cell types and reduces synaptic vesicle endocytosis in vitro. Prevents botulinum A internalization in hippocampal neurons.
  • CAS Number
    1256493-34-1
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₈H₁₄N₂O₅
  • Molecular Weight
    338.31
  • Cell Permeable
    True
  • Purity
    ≥98% by HPLC
  • Solubilities
    >30 mg/ml in DMSO
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    A dynamin inhibitor
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36months
  • PubChem CID
    136227923
  • SMILES
    C1=CC=C2C=C(C(=CC2=C1)C(=O)NN=CC3=CC(=C(C=C3O)O)O)O
  • InChi
    InChI=1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+
  • InChi Key
    UAXHPUSKEWEOAP-DJKKODMXSA-N
  • MSDS Available
    True
  • Gene target
  • Short name
    Hydroxy Dynasore
  • Alternative name
    Hydroxy Dynasore
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