Hydroxy Dynasore
-
Catalog numberB2642-25
-
PricePlease ask
-
Size25 mg
-
-
Alternative_nameDyngo 4a, 3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide
-
DescriptionHydroxy Dynasore is an analog of Dynasore (Cat. No. 1900) that acts as a potent dynamin inhibitor (IC₅₀ values are 0.38 and 2.6 μM for dynamin 1 and 2 respectively). Inhibits dynamin-mediated endocytosis in multiple cell types and reduces synaptic vesicle endocytosis in vitro. Prevents botulinum A internalization in hippocampal neurons.
-
CAS Number1256493-34-1
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC₁₈H₁₄N₂O₅
-
Molecular Weight338.31
-
Cell PermeableTrue
-
Purity≥98% by HPLC
-
Solubilities>30 mg/ml in DMSO
-
HandlingDo not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
-
Tag LineA dynamin inhibitor
-
Storage Condition-20ºC
-
Shipping ConditionGel Pack
-
Shelf Life36months
-
PubChem CID136227923
-
SMILESC1=CC=C2C=C(C(=CC2=C1)C(=O)NN=CC3=CC(=C(C=C3O)O)O)O
-
InChiInChI=1S/C18H14N2O5/c21-14-8-17(24)16(23)7-12(14)9-19-20-18(25)13-5-10-3-1-2-4-11(10)6-15(13)22/h1-9,21-24H,(H,20,25)/b19-9+
-
InChi KeyUAXHPUSKEWEOAP-DJKKODMXSA-N
-
MSDS AvailableTrue
-
Gene target
-
Short nameHydroxy Dynasore
-
Alternative nameHydroxy Dynasore
-