Y-320

Alternative_name

1-(4-chlorophenyl)-N-[3-cyano-4-[4-(4-morpholinyl)-1-piperidinyl]phenyl]-5-methyl-1H-pyrazole-4-carboxamide
Description

Y-320 is an immunomodulator. Y-320 inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM.
CAS Number

288250-47-5
Structure Available

Yes
Molecular Formula

C₂₇H₂₉ClN₆O₂
Molecular Weight

505.01
Cell Permeable

Yes
Purity

≥98% by HPLC
Solubilities

DMSO
Handling

Protect from air and light
Tag Line

An immunomodulator
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

36 months
PubChem CID

22227931
PubChem CID Link
SMILES

CC1=C(C=NN1C2=CC=C(C=C2)Cl)C(=O)NC3=CC(=C(C=C3)N4CCC(CC4)N5CCOCC5)C#N
InChi

InChI=1S/C27H29ClN6O2/c1-19-25(18-30-34(19)24-5-2-21(28)3-6-24)27(35)31-22-4-7-26(20(16-22)17-29)33-10-8-23(9-11-33)32-12-14-36-15-13-32/h2-7,16,18,23H,8-15H2,1H3,(H,31,35)
InChi Key

BWZNJVZTAWBIFG-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes

Identity

HGNC:9543
Gene

PSMB6
Long gene name

proteasome 20S subunit beta 6
Synonyms gene name
- proteasome (prosome, macropain) subunit, beta type, 6
- proteasome subunit beta 6
Synonyms
- Y
- DELTA
Synonyms name
- proteasome subunit β1
GenBank acession
- BC000835
Locus

17p13.2
Discovery year

1995-05-03
Entrez gene record

5694
Pubmed identfication
- 8066462
- 1888762
RefSeq identity
- NM_002798
Classification
- Proteasome
VEGA ID

OTTHUMG00000090777

Identity

HGNC:11065
Gene

SLC7A7
Long gene name

solute carrier family 7 member 7
Synonyms gene
- LPI
Synonyms gene name
- solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
Synonyms
- y+LAT-1
GenBank acession
- AF092032
Locus

14q11.2
Discovery year

1999-01-28
Entrez gene record

9056
Pubmed identfication
- 9829974
RefSeq identity
- NM_003982
Classification
- Solute carriers
VEGA ID

OTTHUMG00000028692
Locus Specific Databases
- LRG_695