Atorvastatin

• Catalog number
  2278-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  2-​(4-​fluorophenyl)-​βR,​δR-​dihydroxy-​5-​(1-​methylethyl)-​3-​phenyl- ​4-​[(phenylamino)carbonyl]-​1H-​pyrrole-​1-​heptanoic acid
• Description
  A cholesterol lowering drug and a competitive inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl coenzyme A) reductase (IC₅₀ = 154 nM) a rate limiting enzyme in cholesterol synthesis. Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. In addition to inhibiting cholesterol synthesis, atorvastatin reduces the production of low-density lipoprotein (LDL).
• CAS Number
  134523-00-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₃₃H₃₅FN₂O₅
• Molecular Weight
  558.64
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO (~15 mg/ml) or EtOH (~0.5 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A potent HMG-CoA reductase inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD00899261
• PubChem CID
  60823
• PubChem CID Link
• SMILES
  CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)O)O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4
• InChi
  InChI=1S/C33H35FN2O5/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40)/t26-,27-/m1/s1
• InChi Key
  XUKUURHRXDUEBC-KAYWLYCHSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Atorvastatin  
• Short name
  Atorvastatin
• Alternative name
  Atorvastatin

Product images

Similar products