Sulfo-SMCC

• Catalog number
  2320-100
• Price
  Please ask
• Size
  100 mg

• Alternative_name
  4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt
• Description
  KEY FEATURES: • Amine reactive Sulfo-NHS ester that crosslinks efficiently with primary amine-containing molecules • Has a maleimide functional group that can be utilized to react specifically with cysteines or sulfhydryl (-SH) groups • Water-soluble; can be used under physiologic conditions • Has a spacer arm length of 8.3 Å (9 atom) • Unlike other maleimide-activated antibodies, those made with Sulfo-SMCC crosslinkers are often more stable, due to the inductive stabilizing effects of the cyclohexyl ring moeity APPLICATIONS: • Routinely used to prepare hapten-carrier protein and antibody-enzyme conjugates, such as HRP conjugation. • Wide range of uses for both small molecule reactions and large biomolecule applications.
• CAS Number
  92921-24-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₆H₁₇N₂NaO₉S
• Molecular Weight
  436.37
• Cell Permeable
  No
• Purity
  ≥90% by NMR
• Solubilities
  H₂O (>10 mg/ml)
• Handling
  Protect from moisture
• Tag Line
  A water-soluble heterobifunctional protein crosslinker
• Storage Condition
  -20 ̊C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00054978
• PubChem CID
  4618794
• PubChem CID Link
• SMILES
  C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]
• InChi
  InChI=1S/C16H18N2O9S.Na/c19-12-5-6-13(20)17(12)8-9-1-3-10(4-2-9)16(23)27-18-14(21)7-11(15(18)22)28(24,25)26;/h5-6,9-11H,1-4,7-8H2,(H,24,25,26);/q;+1/p-1
• InChi Key
  VUFNRPJNRFOTGK-UHFFFAOYSA-M
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Sulfo-SMCC  
• Gene symbol
  CNN1, TAGLN
• Short name
  Sulfo-SMCC
• Alternative name
  Sulfo-SMCC

Gene info

• Identity
  HGNC:2155
• Gene
  CNN1
• Long gene name
  calponin 1
• Synonyms gene name
  • calponin 1, basic, smooth muscle
• Synonyms
  • SMCC
  • Sm-Calp
• GenBank acession
  • U37019
• Locus
  19p13.2
• Discovery year
  1996-08-16
• Entrez gene record
  1264
• Pubmed identfication
  • 8526917
  • 9332369
• RefSeq identity
  • NM_001299
• VEGA ID
  OTTHUMG00000182033

Gene info

• Identity
  HGNC:11553
• Gene
  TAGLN
• Long gene name
  transgelin
• Synonyms
  • SM22
  • WS3-10
  • TAGLN1
  • SMCC
  • DKFZp686P11128
• Synonyms name
  • SM22-alpha
  • transgelin variant 2
• GenBank acession
  • M95787
• Locus
  11q23.3
• Discovery year
  1998-01-16
• Entrez gene record
  6876
• Pubmed identfication
  • 8117285
  • 1520290
• RefSeq identity
  • NM_001001522
• VEGA ID
  OTTHUMG00000167067

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