IQGAP1 Antibody

• Catalog number
  F45144-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  IQGAP1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the IQGAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This IQGAP1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P46940
• Purity
  Antigen affinity
• Description
  This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
• Immunogen
  A portion of amino acids 256-285 from the human protein was used as the immunogen for this IQGAP1 antibody.
• Storage
  Aliquot the IQGAP1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IQGAP1  
• Gene symbol
  IQGAP1
• Short name
  Anti-IQGAP1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to IQGAP1
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6110
• Gene
  IQGAP1
• Long gene name
  IQ motif containing GTPase activating protein 1
• Synonyms
  • p195
  • KIAA0051
  • SAR1
  • HUMORFA01
• Synonyms name
  • RasGAP-like with IQ motifs
• GenBank acession
  • D29640
• Locus
  15q26.1
• Discovery year
  1999-07-23
• Entrez gene record
  8826
• Pubmed identfication
  • 8051149
  • 8670801
• RefSeq identity
  • NM_003870
• Classification
  • IQ motif containing GTPase activating protein family
• VEGA ID
  OTTHUMG00000149832

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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