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Target antigen
SFRP2
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human, mouse, rat
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Analyses
WB,ELISA
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Immunogen
E.coli-derived human SFRP2 recombinant protein (Position: L104-C295). Human SFRP2 shares 99% amino acid (aa) sequence identity with mouse SFRP2.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the SFRP2 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The SFRP2 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
SFRP2 is also known as FRP-2, SARP1 or SDF-5. It is Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.
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Related articles
1. Hao XW, et al. Epigenetic inactivation of secreted frizzled-related protein 2 in esophageal squamous cell carcinoma. World J Gastroenterol, 2012 Feb 14. 2. O'Hurley G, et al. The role of secreted frizzled-related protein 2 expression in prostate cancer. Histopathology, 2011 Dec. 3. Sui C, et al. Variation risks of SFRP2 hypermethylation between precancerous disease and colorectal cancer. Tumour Biol, 2014 Oct.
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Gene Name
SFRP2
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Protein Name
Secreted frizzled-related protein 2
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Gene Full Name
secreted frizzled-related protein 2
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Synonyms
AI851596 antibody|Frizzled related protein 2 antibody|FRP 2 antibody|FRP-2 antibody|FRP2 antibody|MGC128911 antibody|MGC153618 antibody|MGC53344 antibody|SARP 1 antibody|SARP-1 antibody|SARP1 antibody|SDF 5 antibody|SDF5 antibody|Secreted apoptosis related protein 1 antibody|Secreted apoptosis-related protein 1 antibody|Secreted frizzled related protein 2 antibody|Secreted frizzled-related protein 2 antibody|sFRP 2 antibody|sFRP-2 antibody|SFRP2 antibody|Sfrp2 protein antibody|SFRP2_HUMAN antibody
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Uniprot ID
Q96HF1
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Entrez GeneID
6423
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
