CXCR6/BONZO Antibody, ALEXA FLUOR 488

• Catalog number
  bs-1628R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  CXCR6/BONZO Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-CXCR6/BONZO PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CXCR6/BONZO
• Specificity
  This is a highly specific antibody against CXCR6/BONZO.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  141-164/342
• Subcellular location
  Helical, Transmembrane
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CXCR6
• Gene ID Number
  10663
• Swiss Prot
  O00574
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Human Immunodeficiency Virus (HIV) and Simian Immunodeficiency Virus (SIV) require coreceptors to enter and infect target cells. They are dependent upon an interaction between the viral envelope glycoprotein with T cell antigen T4 (CD4) and a G protein coupled receptor (GPCR). HIV1 infection relies upon interaction with a chemokine receptor, usually chemokine (C-C) receptor 5 (CCR5). During progression of the infection, the virus tends to rely upon chemokine (C-X-C) receptor 4 (CXCR4). SIV also utilizes CCR5 in the early stages of infection, but during progression it tends to rely on two orphan GPCR's named chemokine (C-X-C) receptor 6 (Bonzo) and G protein coupled receptor 15 (BOB/GRP15). Bonzo mRNA expression has been localized to lymphoid tissues and activated peripheral blood lymphocytes.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  BONZO; CD186; STRL33; TYMSTR; C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; CXCR6
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-CXCR6/BONZO has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  CXCR6/BONZO  
• Gene symbol
  CXCR6
• Short name
  Anti-CXCR6/BONZO
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  CXCR6/BONZO Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-X-C motif) receptor 6, BONZO and CD186 and STRL33 and TYMSTR, CXCR6 and IDBG-29993 and ENSG00000172215 and 10663, C-X-C chemokine receptor activity, Plasma membranes, Cxcr6 and IDBG-206490 and ENSMUSG00000048521 and 80901, CXCR6 and IDBG-646261 and ENSBTAG00000015708 and 506807

Gene info

• Identity
  HGNC:16647
• Gene
  CXCR6
• Long gene name
  C-X-C motif chemokine receptor 6
• Synonyms gene name
  • chemokine (C-X-C motif) receptor 6
• Synonyms
  • TYMSTR
  • STRL33
  • BONZO
  • CD186
• GenBank acession
  • AF007545
• Locus
  3p21.31
• Discovery year
  2002-08-23
• Entrez gene record
  10663
• Pubmed identfication
  • 9166430
  • 9230441
• Classification
  • C-X-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000133448

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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