CHMP4B+CHMP4C Antibody, ALEXA FLUOR 647

• Catalog number
  bs-7744R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  CHMP4B+CHMP4C Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-CHMP4B+CHMP4C PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  CHMP4B+CHMP4C
• Specificity
  This is a highly specific antibody against CHMP4B+CHMP4C.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  95-137/224
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CHMP4B/CHMP4C
• Gene ID Number
  128866, 92421
• Swiss Prot
  Q9H444, Q96CF2
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  CHMP4B: Charged multivesicular body protein 4b, Chromatin-modifying protein 4b, CHMP4b, SNF7 homolog associated with Alix 1, SNF7-2, hSnf7-2, Vacuolar protein sorting-associated protein 32-2, Vps32-2, hVps32-2 CHMP4C: Charged multivesicular body protein 4c, Chromatin-modifying protein 4c, CHMP4c, SNF7 homolog associated with Alix 3 SNF7-3, hSnf7-3, Vacuolar protein sorting-associated protein 32-3, Vps32-3, hVps32-3
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-CHMP4B+CHMP4C exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  CHMP4B+CHMP4C  
• Gene symbol
  CHMP4C, CHMP4B
• Short name
  Anti-CHMP4B+CHMP4C
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  CHMP4B+CHMP4C Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:30599
• Gene
  CHMP4C
• Long gene name
  charged multivesicular body protein 4C
• Synonyms gene name
  • chromatin modifying protein 4C
• Synonyms
  • MGC22825
  • Shax3
  • VPS32C
• Synonyms name
  • Snf7 homologue associated with Alix 3
• GenBank acession
  • AK000049
• Locus
  8q21.13
• Discovery year
  2005-04-04
• Entrez gene record
  92421
• Pubmed identfication
  • 12860994
  • 14678797
• RefSeq identity
  • NM_152284
• Classification
  • Charged multivesicular body proteins
  • ESCRT-III
• VEGA ID
  OTTHUMG00000164726

Gene info

• Identity
  HGNC:16171
• Gene
  CHMP4B
• Long gene name
  charged multivesicular body protein 4B
• Synonyms gene
  • C20orf178
• Synonyms gene name
  • chromosome 20 open reading frame 178
  • chromatin modifying protein 4B
• Synonyms
  • dJ553F4.4
  • Shax1
  • SNF7-2
  • VPS32B
• GenBank acession
  • AL050349
• Locus
  20q11.22
• Discovery year
  2001-07-17
• Entrez gene record
  128866
• Pubmed identfication
  • 14678797
• Classification
  • ESCRT-III
  • Charged multivesicular body proteins
• VEGA ID
  OTTHUMG00000032272

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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