Galectin-1, human recombinant

• Catalog number
  4648-1000
• Price
  Please ask
• Size
  1 mg

• Synonyms
  Galectin-1, Lectin galactoside-binding soluble 1, β-galactoside- binding lectin L-14-I, Lactose-binding lectin 1, S-Lac lectin 1, Galaptin, 14 kDa lectin, HPL, HBL, Putative MAPK-activating protein PM12, GBP, DKFZp686E23103
• Alternative_names
  Galectin-1, Lectin galactoside-binding soluble 1, β-galactoside- binding lectin L-14-I, Lactose-binding lectin 1, S-Lac lectin 1, Galaptin, 14 kDa lectin, HPL, HBL, Putative MAPK-activating protein PM12, GBP, DKFZp686E23103
• Description
  Modulates cell–cell and cell–matrix interactions
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Biological activity
  Determined by its ability to chemoattract human blood monocytes. Chemotactic activity was observed at a concentration of 2.5 µg/ml with a peak response obtained at 250 µg/ml.
• Results
  2.5 µg/ml
• Molecular Weight
  14.5 kDa
• Storage Temp
  -20°C
• Shipping
  Gel pack
• Shelf Life
  12 months
• Appearance
  Lyophilized protein
• Physical form description
  Sterile filtered and lyophilized from 20 mM Tris, pH 7.5.
• Reconstitution Instructions
  Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°for future use.
• Background Information
  Galectin-1 belongs to growing family of evolutionary conserved animal lectins. Galectins consists of β-galactoside binding lectins that contain homologous carbohydrate recognition domains (CRDs). Galectin-1 has the ability to induce apoptosis of activated T-cells and T-leukaemia cell lines. Other activities include cell differentiation and inhibition activity of CD45 protein phosphatase activity. Galectin also binds β-galactoside as well as CD45, CD3 and CD4. Recombinant Human Galectin is a 14.5 kDa protein consisting of 134 amino acid residues.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Galectin-1  
• Gene symbol
  LGALS1, LGALS8
• Short name
  Galectin-1, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Galectin-1, H. sapiens Rec.
• Alternative technique
  rec

Gene info

• Identity
  HGNC:6561
• Gene
  LGALS1
• Long gene name
  galectin 1
• Synonyms gene name
  • lectin, galactoside-binding, soluble, 1
• Synonyms
  • GBP
• Locus
  22q13.1
• Discovery year
  1991-09-13
• Entrez gene record
  3956
• Pubmed identfication
  • 1988031
  • 12271131
• RefSeq identity
  • NM_002305
• Classification
  • Receptor ligands
  • Galectins
• VEGA ID
  OTTHUMG00000150661

Gene info

• Identity
  HGNC:6569
• Gene
  LGALS8
• Long gene name
  galectin 8
• Synonyms gene name
  • lectin, galactoside-binding, soluble, 8
• Synonyms
  • PCTA-1
• GenBank acession
  • X91790
• Locus
  1q43
• Discovery year
  1995-05-25
• Entrez gene record
  3964
• Pubmed identfication
  • 7852431
  • 8692978
• RefSeq identity
  • NM_006499
• Classification
  • Galectins
• VEGA ID
  OTTHUMG00000039953

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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