IL-33 Recombinant Protein
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Catalog number
40-429
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Price
Please ask
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Size
0.002 mg, 0.01 mg
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About recombinant protein
IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Recombinant murine IL-33 is a 17.5 kDa protein containing 158 amino acid residues.
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Other name of the recombinant
Il-33, Il1f11, NF-HEV, 9230117N10Rik, Interleukin-33, IL-33
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Recombinant in
E. coli
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SEQUENCE
SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSKI
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Activity
The ED50 was determined by the dose - dependent stimulation of the proliferation of murine D10S cells is ≤ 0.5 ng/mL, corresponding to a specific activity of ≥ 2 x 106 units/mg.
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Keep at
The lyophilized IL-33 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-33 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-33 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Rec PROTEIN GI
257900495
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Accession nr
NP_001158196.1
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Pureity
Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
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About
This product is for research use only.
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Protein s origin
Murine
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Vial
Lyophilized
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NCBI ID
77125
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Gene name
interleukin 33
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Source
Mus musculus
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Uniprot
Q8BVZ5
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
Il33
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Short name
IL-33 Recombinant Protein
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative name
Interleukin-33 Rec. Protein
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Alternative technique
rec
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Gene info
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Identity
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Gene
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Long gene name
interleukin 33
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Synonyms gene
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Synonyms gene name
- chromosome 9 open reading frame 26 (NF-HEV)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2003-12-18
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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