Cancer Cell Stemness Inhibitor I

  • Catalog number
    2476-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    2-Acetylnaphtho[2,3-b]furan-4,9-dione; BBI608
  • Description
    A potent small molecule anticancer agent that prevents self-renewal in Cancer Stem Cells (CSCs). Also induces cell death in CSCs and non-stem cancer cells.
  • CAS Number
    83280-65-3
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₄H₈O₄
  • Molecular Weight
    240.21
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A Cancer Cell Stemness inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • PubChem CID
    10331844
  • SMILES
    O=C1C2=C(C=C(C(C)=O)O2)C(C3=C1C=CC=C3)=O
  • InChi
    InChI=1S/C14H8O4/c1-7(15)11-6-10-12(16)8-4-2-3-5-9(8)13(17)14(10)18-11/h2-6H,1H3
  • InChi Key
    DPHUWDIXHNQOSY-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Additional description
    For cells, cell lines and tissues in culture till half confluency. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
  • Gene target
  • Short name
    Cancer Stemness Inhibitor I
  • Alternative name
    Cancer cellular Stemness suppressor I
  • Tissue
    cell
  • Disease
    cancer
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