WZ-8040

• Catalog number
  B2205-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide
• Description
  WZ-8040 is a potent EGFR inhibitor that suppresses the growth of EGFR-T790M (a mutation of the gatekeeper T790 residue) containing cell lines and inhibits EGFR phosphorylation.
• CAS Number
  1214265-57-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₄H₂₅ClN₆OS
• Molecular Weight
  481.01
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>20 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent EGFR inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  44607531
• PubChem CID Link
• SMILES
  CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)SC4=CC=CC(=C4)NC(=O)C=C)Cl
• InChi
  InChI=1S/C24H25ClN6OS/c1-3-22(32)27-18-5-4-6-20(15-18)33-23-21(25)16-26-24(29-23)28-17-7-9-19(10-8-17)31-13-11-30(2)12-14-31/h3-10,15-16H,1,11-14H2,2H3,(H,27,32)(H,26,28,29)
• InChi Key
  KIISCIGBPUVZBF-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  WZ-8040  
• Short name
  WZ-8040
• Alternative name
  WZ-8040

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