Pyridoclax

  • Catalog number
    B1817-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    (E)-3'-methyl-3''-styryl-3,2':5',2'':5'',3'''-quaterpyridine; MR29072
  • Description
    Pyridoclax(MR-29072) is a potent Mcl-1 inhibitor (Kd = 25 nM).  Pyridoclax is able to disrupt BimL/Mcl-1 interaction in whole living cells.
  • CAS Number
    1651890-44-6
  • Structure Available
    Yes
  • Molecular Formula
    C₂₉H₂₂N₄
  • Molecular Weight
    426.51
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent Mcl-1 inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • PubChem CID
    92042827
  • SMILES
    CC1=C(N=CC(=C1)C2=C(C=C(C=N2)C3=CN=CC=C3)C=CC4=CC=CC=C4)C5=CN=CC=C5
  • InChi
    InChI=1S/C29H22N4/c1-21-15-27(20-32-28(21)25-10-6-14-31-18-25)29-23(12-11-22-7-3-2-4-8-22)16-26(19-33-29)24-9-5-13-30-17-24/h2-20H,1H3/b12-11+
  • InChi Key
    WGGSYXQFYRWBEC-VAWYXSNFSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Pyridoclax
  • Alternative name
    Pyridoclax
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