Pyridoclax
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Catalog numberB1817-5
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PricePlease ask
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Size5 mg
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Alternative_name(E)-3'-methyl-3''-styryl-3,2':5',2'':5'',3'''-quaterpyridine; MR29072
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DescriptionPyridoclax(MR-29072) is a potent Mcl-1 inhibitor (Kd = 25 nM). Pyridoclax is able to disrupt BimL/Mcl-1 interaction in whole living cells.
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CAS Number1651890-44-6
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Structure AvailableYes
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Molecular FormulaC₂₉H₂₂N₄
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Molecular Weight426.51
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA potent Mcl-1 inhibitor
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID92042827
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SMILESCC1=C(N=CC(=C1)C2=C(C=C(C=N2)C3=CN=CC=C3)C=CC4=CC=CC=C4)C5=CN=CC=C5
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InChiInChI=1S/C29H22N4/c1-21-15-27(20-32-28(21)25-10-6-14-31-18-25)29-23(12-11-22-7-3-2-4-8-22)16-26(19-33-29)24-9-5-13-30-17-24/h2-20H,1H3/b12-11+
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InChi KeyWGGSYXQFYRWBEC-VAWYXSNFSA-N
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MSDS AvailableYes
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Gene target
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Short namePyridoclax
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Alternative namePyridoclax
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