Recombinant Human Defensin / Beta-defensin 3 / DEFB103 Protein (His tag)

#

• Catalog number
  PKSH031389-50µg
• Price:

  Please ask

  Ask for price
• Size
  50µg

# #

• Synonym
  BD-3;DEFB-3;DEFB103;DEFB3;hBD-3;HBD3;HBP-3;HBP3
• Activity
  NA
• Sequence
  Gly 23-Lys 67
• Fusion tag
  N-His
• Accession
  P81534
• Expressed Host
  E. coli
• Shipping
  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
• Purity
  ＞99 % as determined by SDS-PAGE
• Endotoxin
  Please contact us for more information.
• Stability and Storage
  Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Mol Mass
  7.3 kDa
• AP Mol Mass
  12 kDa
• Formulation
  Lyophilized from sterile 50mM Tris, 0.3% Ttiton X-100, 0.3% SKL, pH 8.5
• Background
  Beta-defensin 3 is a member of the defensin family. Defensin family is comprised by microbicidal and cytotoxic peptides made by neutrophils. Members of the beta-defensin 3 family are highly similar in protein sequence. Beta-defensin 3 shows antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Beta-defensin 3 is abundantly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. It is also expressed in salivary gland, bone marrow, colon, stomach, polyp and larynx. However, in small intestine, it cannot be detected. Defensin has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense. Beta-defensin 3 kills multiresistant S.aureus and vancomycin-resistent E.faecium. It has no significant hemolytic activity.
• Technical data
• Description
  human, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin.
• Conjugation
  histidine
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

#

• Gene target
  Defensin   Beta-defensin   DEFB103   Protein   His   tag  
• Gene symbol
  DEFB103A
• Short name
  Recombinant Defensin / Beta-defensin 3 / DEFB103 Protein (His tag)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
• Label
  His
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Defensin / b-defensin 3 / DEFB103 Protein (histidine detection labelled)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:15967
• Gene
  DEFB103A
• Long gene name
  defensin beta 103A
• Synonyms gene
  • DEFB3
  • DEFB103
• Synonyms gene name
  • defensin, beta 3
  • defensin, beta 103A
• Synonyms
  • HBD-3
  • HBP-3
  • HBD3
  • HBP3
  • DEFB-3
• Synonyms name
  • beta defensin 3
  • beta defensin-3
  • beta-defensin 3
• GenBank acession
  • AF217245
• Locus
  8p23.1
• Discovery year
  2001-06-25
• Entrez gene record
  414325
• Pubmed identfication
  • 11223260
  • 11085990
• RefSeq identity
  • NM_001081551
• Classification
  • Defensins, beta
• VEGA ID
  OTTHUMG00000143855

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products